Company Names, addresses, dates: ^1,2,3
  James L. Avis, Druggist, Main St, Harrisonburg VA (1869-1911)
  James L. Avis, Druggist, 83 S. Main St, Harrisonburg (1912-1927) VA
  Avis' Drug Store, 83 S. Main St., Harrisonburg VA (1927-1940)

Notes:
James Little Avis (1844-1927)⁴ was the son of Captain John Avis, who was the sheriff of Jefferson County VA (now West Virginia). James took part in the capture of abolishionist John Brown in 1859. James served in Stonewall Jackson's brigade in the civil war. He came to Harrisonburg in 1869 and started his drug store, which he ran for about 57 years. ¹

His store was previously owned by Dr. S.M. Dold, and was located between the American and Hill's Hotel. ⁵
I don't know exactly where that was, but I suspect it was at 83 South Main Street, which is the address where it shows up in directories starting in 1912 (earlier directories simply said "Main street" if they had any address at all).

James L. Avis was president of the Virginia Pharmacists Association in 1897 & 1898⁶.

James passed away in 1927, at which time his son, Payne M Avis, ran the drugstore. The drugstore lasted until 1940².

Bottles:

	Clear 3.6" bottle embossed: vertical: JAMES L. AVIS / DRUGGIST / HARRISONBURG VA base: W T & CO / D
	Clear 2.75" bottle embossed: vertical: AVIS' DRUG STORE / HARRISONBURG, VA. base: PAT JUNE 19 88 / T 8A
	Clear (badly cracked) 4.1" bottle embossed: vertical: AVIS' DRUG STORE / HARRISONBURG, VA. base: PAT JUNE 19 88 / SB

These are cardboard boxes. I suspect they held pills, as they have handwriting that looks like a prescription. Both are printed on the bottom of the label with: printed on the bottom of label: JAMES L. AVIS / DRUGGIST / No 83 S. Main St., Harrisonburg, Va.